Physical Functioning & Fatigue In MS

Estimating MCID for PROMISĀ® Fatigue and Physical Function Measures among People with Multiple Sclerosis

Fatigue and effects on physical function are central to the experience of MS for many individuals. The purpose of this study is to learn how much fatigue and physical function have to change before that change becomes important to persons living with MS. Data collected from this study will help to inform a patient-centered Minimally Clinically Important Difference (MCID). The more this type of measure is understood, the better it can be used in future trials.

Participants in this study will complete one online survey. There will be questions regarding physical function and fatigue, as well as your health, MS, mobility, and emotions.

You may be eligible to participate if you are 18 years of age or older, do not use a wheelchair or scooter to move around, and have been diagnosed with MS. Note: In order to participate in this study, you must be a patient of UW Medicine.

Study procedures can be done remotely or in-person at our clinic.

Participants will be compensated a $50 check for completing the study survey.

The lead investigator of this study is Dagmar Amtmann, PhD. This study is sponsored by Merck Healthcare KGaA.

If you are interested in learning more about the study or finding out if you qualify, please email us at or give us a call at (206) 598-0501.