MAPMye MS

STUDY OVERVIEW

We are conducting this study to better understand how myelin thickness changes in the brain of people living with multiple sclerosis (MS). Myelin is important for nerve health. It is known that as people get older, their ability to repair and maintain myelin tends to decline, which may contribute to disease progression in MS. This study aims to identify factors that may help combat these age-related changes.

WHAT DO I HAVE TO DO?

• Two in-person study visits at the MS Center. One at the beginning of the study and one at the end. During these visits, we will perform functional assessments and a neurological examination to evaluate walking, hand function, thinking, and vision.
• Two MRI scans to assess myelin levels throughout the brain. MRI scans will be performed at the UW South Lake Union (SLU) campus, Bio-Molecular Imaging Center, 850 Republican St., Seattle. Each MRI scan takes about 30 minutes and is charged to the study budget.
• Wear a wrist-worn physical activity tracker (Fitbit) throughout the 6-month study period.
• Complete monthly surveys about your health, physical activity, and sleep.

TO BE ELIGIBLE, ONE MUST

• be between the ages of 50 and 70
• have a diagnosis of MS 
• be able to read and speak English 
• be able to complete study assessments online
• be willing to complete in-person procedures listed above

THIS STUDY IS CURRENTLY RECRUITING

To find out if you are eligible, take the pre-screening survey: https://redcap.link/mapmyems

CONTACT

For more information or to inquire about participating, contact study staff at msstudy@uw.edu or call (206) 598-0501. 

STUDY INFORMATION

Sarah Simmons, MD, PhD is the lead investigator of this study. 

IRB Study ID: STUDY00025928 Date Approved: 06/29/2026 

Clinical Trials.gov: NCT07723599